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Index > Protein center > Eno1(Gene name) > Mouse
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  • Eno1 (Gene name),
  • Alpha-enolase (Protein name ),  ENOA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Eno1(Eno-1);
    Protein name:
    Alpha-enolase;
    Alternative:
    Enolase 1;2-phospho-D-glycerate hydro-lyase;Non-neural enolase(NNE);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. ENO1 interacts with PLG in the neuronal plasma membrane and promotes its activation. The C-terminal lysine is required for this binding (By similarity). In vitro, interacts with several glycolytic enzymes including PKM2, PGM, CKM and aldolase. Also binds troponin, in vitro.
    Function:
    Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses (By similarity). May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.
    Subcellular Location:
    Cytoplasm Cell membrane Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form (By similarity). ENO1 is localized to the M-band.
    Protein Attributes:
    Sequence length:
    434
    Sequence:
    50:
    MSILRIHARE | IFDSRGNPTV | EVDLYTAKGL | FRAAVPSGAS | TGIYEALELR | 
    100:
    DNDKTRFMGK | GVSQAVEHIN | KTIAPALVSK | KVNVVEQEKI | DKLMIEMDGT | 
    150:
    ENKSKFGANA | ILGVSLAVCK | AGAVEKGVPL | YRHIADLAGN | PEVILPVPAF | 
    200:
    NVINGGSHAG | NKLAMQEFMI | LPVGASSFRE | AMRIGAEVYH | NLKNVIKEKY | 
    250:
    GKDATNVGDE | GGFAPNILEN | KEALELLKTA | IAKAGYTDQV | VIGMDVAASE | 
    300:
    FYRSGKYDLD | FKSPDDPSRY | ITPDQLADLY | KSFVQNYPVV | SIEDPFDQDD | 
    350:
    WGAWQKFTAS | AGIQVVGDDL | TVTNPKRIAK | AASEKSCNCL | LLKVNQIGSV | 
    400:
    TESLQACKLA | QSNGWGVMVS | HRSGETEDTF | IADLVVGLCT | GQIKTGAPCR | 
    434:
    SERLAKYNQI | LRIEEELGSK | AKFAGRSFRN | PLAK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Alpha-enolase
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    E1449h
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    ELISA Kit for Mouse Alpha-enolase
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    ELISA Kit for Mouse Alpha-enolase
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    E1449m
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    ELISA Kit for Mouse Alpha-enolase
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    E1449b
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    96T
    ELISA Kit for Mouse Alpha-enolase
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    E1449r
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    96T
    CLIA Kit for Mouse Alpha-enolase
    Cat.:
    U1449c
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    96T
    CLIA Kit for Mouse Alpha-enolase
    Cat.:
    U1449b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Alpha-enolase
    Cat.:
    U1449m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Alpha-enolase
    Cat.:
    U1449h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Alpha-enolase
    Cat.:
    U1449r
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Alpha-enolase
    Polyclonal Antibody for Mouse Alpha-enolase
    Cat.:
    P1449Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Alpha-enolase
    Cat.:
    P1449Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Alpha-enolase
    Polyclonal Antibody for Mouse Alpha-enolase
    Cat.:
    P1449Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Alpha-enolase
    Monoclonal Antibody for Mouse Alpha-enolase
    Monoclonal Antibody for Mouse Alpha-enolase
    Monoclonal Antibody for Mouse Alpha-enolase
    Monoclonal Antibody for Mouse Alpha-enolase
    Protein for Mouse Alpha-enolase
    Protein for Mouse Alpha-enolase
    Protein for Mouse Alpha-enolase
    Protein for Mouse Alpha-enolase
    Protein for Mouse Alpha-enolase

    R&D Technical Data
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    Linearity
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    References
    1. 1.
      "Nucleotide sequences of cDNAs alpha and gamma enolase mRNAs from mouse brain."
      Kaghad M. , Dumont X. , Chalon P. , Lelias J.M. , Lamande N. , Lucas M. , Lazar M. , Caput D.
      Nucleic Acids Res.18:3638-3638(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Kidney.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Czech II.
      strain: FVB/N.
      tissue: Mammary gland.
      tissue: Mammary tumor.
    4. 4.
      Lubec G. , Kang S.U. , Klug S. , Yang J.W. , Zigmond M. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 10-28; 33-50; 61-120; 133-179; 184-193; 203-228; 234-253; 257-262; 270-281; 307-326; 344-358; 373-394 AND 413-420;IDENTIFICATION BY MASS SPECTROMETRY
      strain: C57BL/6.
      strain: OF1.
      tissue: Brain.
      tissue: Hippocampus.
    5. 5.
      "Cholesteryl ester loading of mouse peritoneal macrophages is associated with changes in the expression or modification of specific cellular proteins, including increase in an alpha-enolase isoform."
      Bottalico L.A. , Kendrick N.C. , Keller A. , Li Y. , Tabas I.
      Arterioscler. Thromb.13:264-275(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 60-71; 100-114; 184-198 AND 246-259
      tissue: Macrophage.
    6. 6.
      "Biochemical characterization of the mouse muscle-specific enolase: developmental changes in electrophoretic variants and selective binding to other proteins."
      Merkulova T. , Lucas M. , Jabet C. , Lamande N. , Rouzeau J.-D. , Gros F. , Lazar M. , Keller A.
      Biochem. J.323:791-800(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PKM; PGM; CKM; ALDO AND TROPONIN;DEVELOPMENTAL STAGE
    7. 7.
      "Fibre-type distribution and subcellular localisation of alpha and beta enolase in mouse striated muscle."
      Keller A. , Demeurie J. , Merkulova T. , Geraud G. , Cywiner-Golenzer C. , Lucas M. , Chatelet F.-P.
      Biol. Cell92:527-535(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    8. 8.
      "Proteomic identification of proteins conjugated to ISG15 in mouse and human cells."
      Giannakopoulos N.V. , Luo J.K. , Papov V. , Zou W. , Lenschow D.J. , Jacobs B.S. , Borden E.C. , Li J. , Virgin H.W. , Zhang D.E.
      Biochem. Biophys. Res. Commun.336:496-506(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ISGYLATION
    9. 9.
      "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
      Ballif B.A. , Carey G.R. , Sunyaev S.R. , Gygi S.P.
      J. Proteome Res.7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-44;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    10. 10.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-60; LYS-89; LYS-92; LYS-126; LYS-193; LYS-202; LYS-228; LYS-256; LYS-335; LYS-343 AND LYS-406;SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-60; LYS-89; LYS-228 AND LYS-420;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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