Protein name:
Alpha-enolase ;
Alternative:
Enolase 1 ;2-phospho-D-glycerate hydro-lyase ;Non-neural enolase (NNE) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. ENO1 interacts with PLG in the neuronal plasma membrane and promotes its activation. The C-terminal lysine is required for this binding (By similarity). In vitro, interacts with several glycolytic enzymes including PKM2, PGM, CKM and aldolase. Also binds troponin, in vitro.
Function:
Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses (By similarity). May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.
Subcellular Location:
Cytoplasm
Cell membrane
Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form (By similarity). ENO1 is localized to the M-band.
Protein Attributes:
50:
MSILRIHARE | IFDSRGNPTV | EVDLYTAKGL | FRAAVPSGAS | TGIYEALELR |
100:
DNDKTRFMGK | GVSQAVEHIN | KTIAPALVSK | KVNVVEQEKI | DKLMIEMDGT |
150:
ENKSKFGANA | ILGVSLAVCK | AGAVEKGVPL | YRHIADLAGN | PEVILPVPAF |
200:
NVINGGSHAG | NKLAMQEFMI | LPVGASSFRE | AMRIGAEVYH | NLKNVIKEKY |
250:
GKDATNVGDE | GGFAPNILEN | KEALELLKTA | IAKAGYTDQV | VIGMDVAASE |
300:
FYRSGKYDLD | FKSPDDPSRY | ITPDQLADLY | KSFVQNYPVV | SIEDPFDQDD |
350:
WGAWQKFTAS | AGIQVVGDDL | TVTNPKRIAK | AASEKSCNCL | LLKVNQIGSV |
400:
TESLQACKLA | QSNGWGVMVS | HRSGETEDTF | IADLVVGLCT | GQIKTGAPCR |
434:
SERLAKYNQI | LRIEEELGSK | AKFAGRSFRN | PLAK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Chicken
Mouse
Bovine
Rat
ELISA Kit for Mouse Alpha-enolase
ELISA Kit for Mouse Alpha-enolase
ELISA Kit for Mouse Alpha-enolase
ELISA Kit for Mouse Alpha-enolase
ELISA Kit for Mouse Alpha-enolase
CLIA Kit for Mouse Alpha-enolase
CLIA Kit for Mouse Alpha-enolase
CLIA Kit for Mouse Alpha-enolase
CLIA Kit for Mouse Alpha-enolase
CLIA Kit for Mouse Alpha-enolase
Polyclonal Antibody for Mouse Alpha-enolase
Polyclonal Antibody for Mouse Alpha-enolase
Polyclonal Antibody for Mouse Alpha-enolase
Polyclonal Antibody for Mouse Alpha-enolase
Polyclonal Antibody for Mouse Alpha-enolase
Monoclonal Antibody for Mouse Alpha-enolase
Monoclonal Antibody for Mouse Alpha-enolase
Monoclonal Antibody for Mouse Alpha-enolase
Monoclonal Antibody for Mouse Alpha-enolase
Monoclonal Antibody for Mouse Alpha-enolase
Protein for Mouse Alpha-enolase
Protein for Mouse Alpha-enolase
Protein for Mouse Alpha-enolase
Protein for Mouse Alpha-enolase
Protein for Mouse Alpha-enolase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
2.
"The transcriptional landscape of the mammalian genome."
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Kidney .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Czech II .
strain :
FVB/N .
tissue :
Mammary gland .
tissue :
Mammary tumor .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 10-28; 33-50; 61-120; 133-179; 184-193; 203-228; 234-253; 257-262; 270-281; 307-326; 344-358; 373-394 AND 413-420;IDENTIFICATION BY MASS SPECTROMETRY
strain :
C57BL/6 .
strain :
OF1 .
tissue :
Brain .
tissue :
Hippocampus .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 60-71; 100-114; 184-198 AND 246-259
tissue :
Macrophage .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH PKM; PGM; CKM; ALDO AND TROPONIN;DEVELOPMENTAL STAGE
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ISGYLATION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-44;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Brain .
10.
"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J.
,
Chen Y.
,
Tishkoff D.X.
,
Peng C.
,
Tan M.
,
Dai L.
,
Xie Z.
,
Zhang Y.
,
Zwaans B.M.
,
Skinner M.E.
,
Lombard D.B.
,
Zhao Y.
Mol. Cell50:919-930(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-60; LYS-89; LYS-92; LYS-126; LYS-193; LYS-202; LYS-228; LYS-256; LYS-335; LYS-343 AND LYS-406;SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-60; LYS-89; LYS-228 AND LYS-420;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .